Medical Science Heroes at City of Hope
"Almost 20 years ago, I was approached by 3-time Oscar-winning director, Mark Jonathan Harris to be part of a documentary about a new immune-based therapy for glioblastoma that we were working on at the City of Hope. We were genetically modifying human T-cells outside the body to fight brain cancer. The film, A Delicate Balance holds up very well today. Gene therapy has come a long way. Two new RNA-based vaccines for the ongoing pandemic (Pfizer/BioNTech and Moderna) are a type of gene therapy that works inside the body to activate the immune system to fight COVID19."
Laurence Cooper, M.D., Ph.D.
"Big Zach" Suffers from Mitochondrial Disease
Mitochondria exist in nearly every cell of the human body. It’s responsible for creating 90% of the energy you need to sustain life and support organ function.
However, when mitochondria cannot convert food and oxygen into life-sustaining energy, cell injury and even cell death follow. When this process is repeated throughout the body, organ systems begin to fail and even stop functioning.
"Big Zach" and his loving Mom, Jennifer Haught star in this brief PACIFIC FILM FOUNDATION video about a very special event, "SUPERCHARGED FOR MITO."
See "Ask The MITO Doc" Webcast
Ensuring healthy lives and promoting well-being at all ages is essential to sustainable development. Currently, the world is facing a global health crisis unlike any other — COVID-19 is spreading human suffering, destabilizing the global economy and upending the lives of billions of people around the globe.
Before the pandemic, major progress was made in improving the health of millions of people.
Progress is being made...
Significant strides were made in increasing life expectancy and reducing some of the common killers associated with child and maternal mortality.
But more efforts are needed to fully eradicate a wide range of diseases and address many different persistent and emerging health issues.
By focusing on providing more efficient funding of health systems, improved sanitation and hygiene, and increased access to physicians, significant progress can be made in helping to save the lives of millions.
In 2018 an estimated 6.2 million children and adolescents under the age of 15 years died, mostly from preventable causes. Of these deaths, 5.3 million occurred in the first five years, with almost half of these in the first month of life.
Malnourished children, particularly those with severe acute malnutrition, have a higher risk of death from common childhood illness such as diarrhoea, pneumonia, and malaria. Nutrition-related factors contribute to about 45 per cent of deaths in children under five years of age.
Over 40 per cent of all countries have fewer than 10 medical doctors per 10,000 people; over 55 per cent of countries have fewer than 40 nursing and midwifery personnel per 10,000 people.
Every day in 2017, approximately 810 women died from preventable causes related to pregnancy and childbirth.
94 per cent of all maternal deaths occur in low and lower middle-income countries.
Maternal mortality ratio – the proportion of mothers that do not survive childbirth in underdeveloped regions is still 14 times higher than in the developed regions.
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